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<i>Scn1a</i> -GFP transgenic mouse revealed Nav1.1 expression in neocortical pyramidal tract projection neurons

2021-03-31

Abstract excerpt

Expressions of voltage-gated sodium channels Nav1.1 and Nav1.2, encoded by SCN1A and SCN2A genes respectively, have been reported to be mutually exclusive in most brain regions. In juvenile and adult neocortex, Nav1.1 is predominantly expressed in inhibitory neurons while Nav1.2 is in excitatory neurons. Although a distinct subpopulation of layer V (L5) neocortical excitatory neurons were also reported to expres...

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Literature Corpus work
286dc198-0117-57b0-a669-3d1163b7a350
DOI
10.1101/2021.03.31.437794
Open publication

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<i>Scn1a</i> -GFP transgenic mouse revealed Nav1.1 expression in neocortical pyramidal tract projection neuronsDOI 10.1101/2021.03.31.437794
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