Article

The non-coding<i>GBA1</i>rs3115534 variant is associated with REM sleep behavior disorder in Nigerians

2023-11-07

Abstract excerpt

<h4>Background</h4> Damaging coding variants in GBA1 are a genetic risk factor for rapid eye movement sleep behavior disorder (RBD), which is a known early feature of synucleinopathies. Recently, a population-specific non-coding variant (rs3115534) was found to be associated with PD risk and earlier disease onset in individuals of African ancestry. <h4>Objectives</h4> To investigate whether the GBA1 rs3115534 PD r...

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Literature Corpus work: 284c61c5-a169-5082-af8e-2fd7e04d1d37
DOI: 10.1101/2023.11.07.23298092

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