Article

<i>SMPD1</i> variants do not have a major role in REM sleep behavior disorder

2020-02-18

Abstract excerpt

Mutations in the sphingomyelin phosphodiesterase 1 ( SMPD1 ) gene were reported to be associated with Parkinson disease (PD) and dementia with Lewy bodies (DLB). The majority of patients with isolated rapid eye movement sleep behavior disorder (iRBD) develop PD or DLB later in life, suggesting that iRBD is a prodromal phase of these two conditions. In the current study we aimed to evaluate the role of SMPD1 varian...

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Literature Corpus work: 582fbb14-57e3-59e1-8b3d-ccaa1fca4f49
DOI: 10.1101/2020.02.15.20023374

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