Article

The genome of North American beaver provides insights into the mechanisms of its longevity and cancer resistance

2020-06-27

Abstract excerpt

The North American beaver (Castor canadensis) is an exceptionally long-lived and cancer-resistant rodent species, and thus an excellent model organism for comparative genomic studies of longevity. Here, we utilize a significantly improved beaver genome assembly to assess evolutionary changes in gene coding sequences, copy number, and expression. We found that the beaver Aldh1a1 , a stem cell marker gene encoding...

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Identifiers and source

Literature Corpus work: 2834eea0-5fd9-5cf0-bf3c-7707f882d46e
DOI: 10.1101/2020.06.25.171322

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