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Article

A scan for genes associated with cancer mortality and longevity in pedigree dog breeds.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Aug 2020

Doherty Aoife, Lopes Inês, Ford Christopher T, Monaco Gianni, Guest Patrick, de Magalhães João Pedro

Abstract excerpt

Selective breeding of the domestic dog (Canis lupus familiaris) rigidly retains desirable features, and could inadvertently fix disease-causing variants within a breed. We combine phenotypic data from > 72,000 dogs with a large genotypic dataset to search for genes associated with cancer mortality and longevity in pedigree dog breeds. We validated previous findings that breeds with higher average body weight have...

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Identifiers

PMID: 32661568
DOI: 10.1007/s00335-020-09845-1
PMCID: PMC7496057

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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