Article

KMT2C knockout generates ASD-like behaviors in mice

2023-05-26

Abstract excerpt

<h4>ABSTRACT</h4> Neurodevelopmental disorders have been associated with genetic mutations that affect cellular function, including chromatin regulation and epigenetic modifications. Recent studies in humans have identified mutations in KMT2C, an enzyme responsible for modifying histone tails and depositing H3K4me1 and H3K4me3, as being associated with Kleefstra syndrome 2 and autism spectrum disorder (ASD). Howe...

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Literature Corpus work: 2830a637-cabc-5f9f-9f0b-0fdb04e19d5a
DOI: 10.1101/2023.05.26.542423

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