Article

Identification of biomarkers and pathways of mouse embryonic fibroblasts with the dysfunction of mitochondrial DNA

2021-04-06

Abstract excerpt

Mitochondrial diseases are clinically heterogeneous which involve multiple systems such as organs that are highly dependent on metabolism. Dysfunction of mtDNA is the main cause of mitochondrial diseases that trigger inflammation and immune responses. Here, we aim to identify the biological function and pathways of MEFs with the dysfunction of mtDNA through deletion of YME1L. The gene expression profiles of GSE161...

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Literature Corpus work: 27f37ba7-9c84-560a-b6c8-e3425d2d259f
DOI: 10.1101/2021.04.05.438453

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