Omics analysis revealed the antitumor effect of mitochondrial targeted drug combination

Abstract excerpt

<h4>Purpose: </h4> The incidence and mortality of lung cancer have continued to rise in recent years. Mitochondrial energy metabolism malfunction is crucial for cancer cell death, proliferation and bioenergetic reprogramming. Improving the mitochondrial activity is a potent method to arrest tumor development and growth. In this study, we attempted to use mitochondrial targeting drugs to improve mitochondrial funct...

Topics

Open a Topic to create a Post that cites this publication.

• Autophagy in Disease and Therapy
• Cancer, Hypoxia, and Metabolism
• CRISPR-Cas Systems
• Drug Resistance, Neoplasm
• Energy Metabolism
• Mitochondria
• Mitochondrial Function and Pathology
• Molecular Targeted Therapy

Identifiers and source

Literature Corpus work

8e21d1c1-a794-5823-847c-07407fb309e8

DOI

10.21203/rs.3.rs-2999676/v1