Identification of critical genes and biological signaling for metformin treated liver cancer

Abstract excerpt

Liver cancer is a leading source of cancer-related mortality in the world. A number of studies have shown the correlation of metformin treatment with a decrease in cancer risk. However, the relevant molecules and mechanisms are not clear during the treatment. In this study, our aim is to identify the significant molecules and signaling pathways in the treatment of metformin in liver cancer cells by analyzing the R...

Topics

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• Antineoplastic Agents
• Carcinogenesis
• High-Throughput Nucleotide Sequencing
• Kelch-Like ECH-Associated Protein 1
• Liver Disease Diagnosis and Treatment
• Liver Neoplasms
• Mutation
• NF-E2-Related Factor 2

Identifiers and source

Literature Corpus work

7b504a2d-56dc-5db6-9244-dba5663e939b

DOI

10.1101/2021.12.29.474467