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Article

Pathophysiological role of BACH transcription factors in digestive system diseases

9 May 2023

Abstract excerpt

BTB and CNC homologous (BACH) proteins, including BACH1 and BACH2, are transcription factors that are widely expressed in human tissues. BACH proteins form heterodimers with small musculoaponeurotic fibrosarcoma (MAF) proteins to suppress the transcription of target genes. Furthermore, BACH1 promotes the transcription of target genes. BACH proteins regulate physiological processes, such as the differentiation of...

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PMID: 37228820
DOI: 10.3389/fphys.2023.1121353

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