Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The functional role of Higd1a in mitochondrial homeostasis and in multiple disease processes

22 Apr 2022

Abstract excerpt

is a conserved gene in evolution which is widely expressed in many tissues in mammals. Accumulating evidence has revealed multiple functions of Higd1a, as a mitochondrial inner membrane protein, in the regulation of metabolic homeostasis. It plays an important role in anti-apoptosis and promotes cellular survival in several cell types under hypoxic condition. And the survival of porcine Sertoli cells facilitated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endoplasmic Reticulum Stress and Disease
Share to Liver Disease Diagnosis and Treatment
Share to Mitochondrial Function and Pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37492734
DOI: 10.1016/j.gendis.2022.03.018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The functional role of Higd1a in mitochondrial homeostasis and in multiple disease processesPMID 37492734Read ↗

Mitochondrial dynamics and its impact on human health and diseases: inside the DRP1 blackbox.Semantic proximity Read ↗

Hexokinase domain-containing protein-1 in metabolic diseases and beyondSemantic proximity Read ↗

The roles of IDH1 in tumor metabolism and immunity.Semantic proximity Read ↗

Mitochondrial Dysfunction as a Factor of Energy Metabolism Disorders in Type 2 Diabetes MellitusSemantic proximity Read ↗

MTCH2 in Metabolic Diseases, Neurodegenerative Diseases, Cancers, Embryonic Development and ReproductionSemantic proximity Read ↗

Multiple roles of ALDH1 in health and diseaseSemantic proximity Read ↗

Biosystem Analysis of the Hypoxia Inducible Domain Family Member 2A: Implications in Cancer Biology.Semantic proximity Read ↗

Focused screening of mitochondrial metabolism reveals a crucial role for a tumor suppressor Hbp1 in ovarian reserveSemantic proximity Read ↗

HAX1: A versatile, intrinsically disordered regulatory proteinSemantic proximity Read ↗

Gene symbol: MLH1.Semantic proximity Read ↗

Emerging Roles of NDUFS8 Located in Mitochondrial Complex I in Different Diseases.Semantic proximity Read ↗

CHDH, a key mitochondrial enzyme, plays a diagnostic role in metabolic disorders diseases and tumor progressionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.