Article

Next generation protein-corrole bio-assemblies provide effective tumoricidal treatment in a metastatic triple-negative breast cancer model

2026-02-05

Abstract excerpt

Assemblies that combine chemotherapeutics with tumor-targeting proteins are promising agents for treating resistant cancers but require full biochemical characterization before therapeutic deployment. We developed and optimized a HER3 targeting capsomere, HPK2.0, which forms stable nanoscale assemblies with cytotoxic corroles via electrostatic neutralization and shape complementarity. These nanocomplexes exhibit d...

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Literature Corpus work: 27a0b7c0-7278-5e0c-bbdb-878b9ec3ae21
DOI: 10.64898/2026.02.03.703292

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