Article

Red Blood Cell-derived Extracellular Vesicles enable Cisplatin and Cetuximab combined Therapy against Triple-Negative Breast Cancer

2025-03-20

Abstract excerpt

<h4>Background: </h4> Triple-negative breast cancer is an aggressive breast cancer subtype characterized by the absence of human epidermal growth factor receptor 2, estrogen and progesterone receptors, limiting targeted therapy options. Cisplatin, a chemotherapeutic agent, induces DNA damage and exhibits some efficacy against triple-negative breast cancer, but its effectiveness is often reduced by chemoresistance...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c37fe3e8-c669-59e8-8724-efee56a86136
DOI: 10.1101/2025.03.20.644320

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Red Blood Cell-derived Extracellular Vesicles enable Cisplatin and Cetuximab combined Therapy against Triple-Negative Breast CancerDOI 10.1101/2025.03.20.644320Read

Induction of Ferroptosis by an Amalgam of Extracellular Vesicles and Iron Oxide Nanoparticles Overcomes Cisplatin Resistance in Lung CancerSemantic proximity Read

Drug-resistant extracellular vesicles: a reliable biomarker for predicting therapeutic response in patients with triple-negative breast cancer receiving neoadjuvant chemotherapySemantic proximity Read

Next generation protein-corrole bio-assemblies provide effective tumoricidal treatment in a metastatic triple-negative breast cancer modelSemantic proximity Read

Nanomedicine Strategies to Overcome Multi-Drug Resistance in Cancer: Innovations in Targeted Delivery, Tumor Microenvironment Modulation and Synergistic TherapiesSemantic proximity Read

Enhancing Breast Cancer Therapy: Nanocarrier-Based Targeted Drug DeliverySemantic proximity Read

Next generation protein-corrole bio-assemblies provide effective tumoricidal treatment in a metastatic triple-negative breast cancer modelSemantic proximity Read

Multiaction Platinum(IV) Prodrug Containing Thymidylate Synthase Inhibitor and Metabolic Modifier against Triple-Negative Breast CancerSemantic proximity Read

H-Ferritin-nanocaged olaparib: a promising choice for both BRCA-mutated and sporadic triple negative breast cancerSemantic proximity Read

Extracellular vesicles in anti-tumor drug resistance: Mechanisms and therapeutic prospectsSemantic proximity Read

Redox-Responsive Theranostic Nanoplatforms in Oncology: Linking Tumor Microenvironment Biology, Proteasome Targeting, and Clinical TranslationSemantic proximity Read

pH-Sensitive Shell–Core Platform Block DNA Repair Pathway To Amplify Irreversible DNA Damage of Triple Negative Breast CancerSemantic proximity Read

Ferroptosis by nanomaterials: targeting cancer stem cells and overcoming drug resistanceSemantic proximity Read