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Phagocytosis model of calcium oxalate monohydrate crystals generated using human induced pluripotent stem cell-derived macrophages

2023-12-12

Abstract excerpt

Macrophages play a role in nephrolithiasis, offering the possibility of macrophage-mediated preventive therapies. To establish a system for screening drugs that could prevent the formation of kidney stones, we aimed to develop a model using human induced pluripotent stem cell (iPSC)-derived macrophages to study phagocytosis of calcium oxalate monohydrate (COM) crystals. Human iPSCs (201B7) were cultured. CD14 + mo...

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Literature Corpus work
279cf08d-e3d7-55a2-8547-df0cea52943b
DOI
10.21203/rs.3.rs-3726151/v1
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Phagocytosis model of calcium oxalate monohydrate crystals generated using human induced pluripotent stem cell-derived macrophagesDOI 10.21203/rs.3.rs-3726151/v1
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