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Article

Spontaneous cell fusion in macrophage cultures expressing high levels of the P2Z/P2X7 receptor.

The Journal of cell biology - 11 Aug 1997

Chiozzi P, Sanz J M, Ferrari D, Falzoni S, Aleotti A, Buell G N, Collo G, Di Virgilio F

Abstract excerpt

Mouse and human macrophages express a plasma membrane receptor for extracellular ATP named P2Z/P2X7. This molecule, recently cloned, is endowed with the intriguing property of forming an aqueous pore that allows transmembrane fluxes of hydrophylic molecules of molecular weight below 900. The physiological function of this receptor is unknown. In a previous study we reported experiments suggesting that the...

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Identifiers

PMID: 9245796
DOI: 10.1083/jcb.138.3.697
PMCID: PMC2141639

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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