Article

Rho GTPases signaling mediates aggressiveness and differentiation in neuroblastoma tumors

2024-11-21

Abstract excerpt

<h4>Background</h4> Neuroblastoma (NB) is a pediatric cancer with highly variable outcomes, necessitating improved understanding of the molecular pathways driving its progression. Intratumor cellular heterogeneity related to neural differentiation has emerged as a defining characteristic that can explain its aggressive behavior. Although recurrent driver mutations are not typically observed in these tumors, Rho G...

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Literature Corpus work: 279a9854-14a3-5ce8-aee5-2962dc012d5e
DOI: 10.1101/2024.11.20.624451

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