Article

Single-cell transcriptomics and functional validation reveal a TUBB4B-associated malignant epithelial lineage in Nasopharyngeal Carcinoma

2026-05-06

Abstract excerpt

<title>Abstract</title> <p> Background Intratumoral heterogeneity of malignant epithelial cells limits prognostic stratification and therapeutic development in NPC, yet lineage-resolved malignant programs remain poorly defined. We aimed to identify clinically relevant malignant epithelial states and their associated molecular programs in NPC. Methods Fresh normal nasopharyngeal tissue, primary NPC, and nodal m...

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Literature Corpus work: 244763e6-40d8-5f27-8901-d930ebafe36a
DOI: 10.21203/rs.3.rs-9414524/v1

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Single-cell transcriptomics and functional validation reveal a TUBB4B-associated malignant epithelial lineage in Nasopharyngeal CarcinomaDOI 10.21203/rs.3.rs-9414524/v1Read

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