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Rho GTPase–related prognostic signature for esophageal squamous cell carcinoma identifies and validates CTTN as an independent adverse prognostic factor

2025-12-02

Abstract excerpt

<title>Abstract</title> <p>Background Rho GTPases orchestrate actin dynamics and tumor cell motility, but their prognostic relevance in esophageal squamous cell carcinoma (ESCC) remains unclear. We aimed to identify Rho GTPase–related differentially expressed genes (DEGs), build a prognostic model, evaluate important gene expression against clinicopathological features, and examine CTTN function in vitro. Methods...

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Literature Corpus work
ea3d50aa-aab1-5a7e-93ae-84b7702b200e
DOI
10.21203/rs.3.rs-8143466/v1
Open publication

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Rho GTPase–related prognostic signature for esophageal squamous cell carcinoma identifies and validates CTTN as an independent adverse prognostic factorDOI 10.21203/rs.3.rs-8143466/v1
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