Article

Sperm from infertile, oligozoospermic men have elevated mutation rates

2024-08-22

Abstract excerpt

Male infertility is associated with elevated rates of aneuploidy and DNA breaks in spermatozoa and germline precursors. This common condition is not well understood and is associated with poor individual and familial somatic health relative to fertile men. To further understand the extent and source of genome instability, we used error-corrected duplex DNA sequencing to test whether the impaired spermatogenesis an...

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Literature Corpus work: 27819b54-c06d-5e85-91bf-3a05182076a3
DOI: 10.1101/2024.08.22.24312232

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