Article

Towards In Silico 3-D Structure Modeling and Prioritization of Candidate Genes Regulating the Bovine and Caprine Apelinergic System

2023-05-24

Abstract excerpt

<h4>Background: </h4> The Apelinergic system (consisting of two ligands - APELIN/APELA and its receptor APJ) plays a crucial role in many important biological processes in animals. The human Apelin, Apela and its receptor APJ are well characterized in terms of structure and function, but very little is known about the two ligands and its receptor in bovines and caprine species. The genes related to the Apelinergic...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 277cca32-a361-515e-9415-0a697281e6c6
DOI: 10.21203/rs.3.rs-2858709/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Towards In Silico 3-D Structure Modeling and Prioritization of Candidate Genes Regulating the Bovine and Caprine Apelinergic SystemDOI 10.21203/rs.3.rs-2858709/v1Read

A network map of apelin-mediated signalingSemantic proximity Read

Critical APJ receptor residues in extracellular domains that influence effector selectivity.Semantic proximity Read

Structural and functional determination of peptide versus small molecule ligand binding at the apelin receptorSemantic proximity Read

Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled ReceptorsSemantic proximity Read

Integrative view of serpins in health and disease: the contribution of serpinA3Semantic proximity Read

International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands.Semantic proximity Read

Evaluation of Structure Prediction and Molecular Docking Tools for Therapeutic Peptides in Clinical Use and Trials Targeting Coronary Artery DiseaseSemantic proximity Read

A promising therapeutic peptide and preventive/diagnostic biomarker for age-related diseases: The Elabela/Apela/Toddler peptideSemantic proximity Read

Emerging roles of melanocortin receptor accessory proteins (MRAP and MRAP2) in physiology and pathophysiologySemantic proximity Read

In Silico Predictive Homology Modeling of PKHD-1 Protein: A Comparative Study among Three Different SpeciesSemantic proximity Read

PTPN22 is a Potentially Diagnostic Biomarker for Abdominal Aortic AneurysmSemantic proximity Read

CTRP family in diseases associated with inflammation and metabolism: molecular mechanisms and clinical implicationSemantic proximity Read