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Integrated Metabolomic and Transcriptomic Analysis Identifies Candidate Regulatory Networks in Bone Metabolic Dysregulation of Osteoarthritis

2025-05-13

Abstract excerpt

<title>Abstract</title> <p>Osteoarthritis (OA) represents a prevalent articular condition characterized by significant disturbances in bone metabolic balance, yet the molecular pathways governing these skeletal alterations remain inadequately defined.This study conducted metabolomic and transcriptomic analyses of 30 OA patients and 30 controls, revealing significant alterations in purine, lipid, and amino acid me...

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Literature Corpus work
5bafe4bc-e569-5d8b-9fcb-373c434d9bd9
DOI
10.21203/rs.3.rs-6359791/v1
Open publication

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Integrated Metabolomic and Transcriptomic Analysis Identifies Candidate Regulatory Networks in Bone Metabolic Dysregulation of OsteoarthritisDOI 10.21203/rs.3.rs-6359791/v1
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