Article
Pellino 1 Communicates Intercellular Signaling in Chronic Skin Inflammatory Microenvironment
2018-05-30
Abstract excerpt
Chronic skin inflammation including psoriasis is a multisystem disease, affecting more than 5% of the general population. Here we show that Pellino 1 (Peli1), a signal-responsive ubiquitin E3 ligase, is highly up-regulated in human psoriatic skin lesions and that increased Peli1 expression correlates with the immunopathogenesis of psoriasis-like chronic skin inflammatory disease. Interestingly, Peli1 directly inte...
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Identifiers and source
- Literature Corpus work
- 276923dd-7a79-5a67-a4ab-35391b900b49
- DOI
- 10.1101/334433