Article

A novel bioinformatics pipeline for the identification of immune inhibitory receptors as potential therapeutic targets

2023-10-28

Abstract excerpt

Blocking inhibitory receptors like PD-1 and CTLA-4 has revolutionized cancer treatment in recent years. However, despite major successes in melanoma and lung cancer, the majority of cancer types are not responsive to these immunotherapies. As such, there is an ongoing need for the identification of novel inhibitory receptors as drug targets. Most inhibitory receptors signal via immunoreceptor tyrosine-based inhibi...

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Literature Corpus work: 274c25db-4b9b-5711-9b74-fc19a6532c2b
DOI: 10.1101/2023.10.24.563834

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