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The Effects of The MTHFR 677C>T (Rs1801133) Genetic Variant on Susceptibility and Disability in Multiple Sclerosis Patients are Mediated by Homocysteine But Not Folate Levels

2021-12-15

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<title>Abstract</title> <p>We investigated whether the <italic>MTHFR</italic> 677C>T (rs1801133) variant and plasma homocysteine and folate are associated with multiple sclerosis (MS), disability, disability progression, and inflammatory biomarkers. We included 163 MS patients categorized using the Expanded Disability Status Scale (EDSS) as mild (EDSS<3) and moderate/high (EDSS≥3) disability, and 226 healthy cont...

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Literature Corpus work
26cc6be9-c88c-5bf9-84dc-0c289e8aa5f4
DOI
10.21203/rs.3.rs-947647/v3
Open publication

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