Article
Association of methylenetetrahydrofolate reductase gene C677T polymorphism with multiple sclerosis in Turkish patients.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Dec 2014
Cevik Betul, Yigit Serbulent, Karakus Nevin, Aksoy Durdane, Kurt Semiha, Ates Omer
Abstract excerpt
BACKGROUND AND AIM: Multiple sclerosis (MS) is a chronic neurodegenerative autoimmune disease of the central nervous system. Genetic risk factors are known to contribute to the etiology of MS. Methylenetetrahydrofolate reductase (MTHFR) gene C677T polymorphism has been associated with susceptibility to various autoimmune diseases. The aim of this study was to investigate a possible association between the MTHFR...
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