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Article

Association of methylenetetrahydrofolate reductase A1298C polymorphism but not of C677T with multiple sclerosis in Tunisian patients.

Clinical neurology and neurosurgery - 1 Sept 2013

Fekih Mrissa Najiba, Mrad Meriem, Klai Sarra, Zaouali Jamel, Sayeh Aycha, Mazigh Chakib, Nsiri Brahim, Machgoul Salem, Gritli Nasreddine, Mrissa Ridha

Abstract excerpt

BACKGROUND AND OBJECTIVE: Multiple sclerosis (MS) is a chronic neurological disease characterized by central nervous system (CNS) inflammation and demyelination of nerve axons. The aim of this study was to investigate a possible association between the methylenetetrahydrofolate reductase (MTHFR) gene and multiple sclerosis in Tunisian patients. PATIENTS AND METHODS: The genotyping of two missense variants of the...

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Source

Identifiers

PMID: 23523621
DOI: 10.1016/j.clineuro.2013.02.025

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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