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Article

Polymorphisms CYP2R1 rs10766197 and CYP27B1 rs10877012 in Multiple Sclerosis: A Case-Control Study.

Journal of immunology research - 1 Jan 2021

Martinez-Hernandez A, Perez-Guerrero E E, Macias-Islas M A, Nava-Valdivia C A, Villagomez-Vega A, Contreras-Haro B, Garcia-Ortega Y E, Esparza-Guerrero Y, Gallardo-Moya S G, Gamez-Nava J I, Gonzalez-Lopez L, Oliva-Flores E, Rodriguez-Jimenez N A, Cortes-Enriquez F, Saldaña-Cruz A M

Abstract excerpt

BACKGROUND: Multiple sclerosis (MS) is a chronic autoimmune inflammatory disease. Low vitamin D levels have been reported to be a risk factor for MS, and genetic variances could be implicated. The aim of this study was to evaluate the association of MS with rs10766197 polymorphism of CYP2R1 gene and rs10877012 polymorphism of CYP27B1 gene. The second aim was to analyse whether these polymorphisms are associated...

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Identifiers

PMID: 34977256
DOI: 10.1155/2021/7523997
PMCID: PMC8718303

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