Article

Integrating central and peripheral neurons in elongating multi-lineage-organized gastruloids

2020-12-30

Abstract excerpt

<h4>ABSTRACT</h4> Human stem cell technologies including self-assembling 3D tissue models provide unprecedented access to early neurodevelopment and enable fundamental insights into neuropathologies. Gastruloid models have yet to be used to investigate the developing nervous system. Here we generate elongating multi-lineage-organized (EMLO) gastruloids with trunk identity that co-develop central and peripheral ne...

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Literature Corpus work: 264f20fa-92af-5da2-a927-c146dd434cf9
DOI: 10.1101/2020.12.29.424774

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