Article

Self-organizing human heart assembloids with autologous and developmentally relevant cardiac neural crest-derived tissues

2024-12-11

Abstract excerpt

<h4>ABSTRACT</h4> Neural crest cells (NCCs) are a multipotent embryonic cell population of ectodermal origin that extensively migrate during early development and contribute to the formation of multiple tissues. Cardiac NCCs play a critical role in heart development by orchestrating outflow tract septation, valve formation, aortic arch artery patterning, parasympathetic innervation, and maturation of the cardiac...

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Literature Corpus work: d07c1c1f-a2d0-5a90-a974-2c42ae13bcd6
DOI: 10.1101/2024.12.11.627627

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