InCytokine, an open-source software, reveals a TREM2 variant specific cytokine signature

Abstract excerpt

Cytokine and chemokine profiling is central to understanding inflammatory processes and the mechanisms driving diverse diseases. We introduce InCytokine, an open-source tool for semiquantitative analysis of cytokine and chemokine data generated by protein array technologies. InCytokine features robust and modular image-processing workflows, including automated spot detection, template alignment, normalization, qua...

Topics

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• Animals, Newborn
• Inflammation
• Inflammation Mediators
• Membrane Glycoproteins
• Microglia
• Receptors, Immunologic
• RNA-Seq
• STAT6 Transcription Factor

Identifiers and source

Literature Corpus work

264f10e4-50c0-5eda-9900-72a7dc849b89

DOI

10.1101/2025.10.31.685741