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Article

TTC7A: Steward of Intestinal Health

13 Dec 2018

Abstract excerpt

The increasing incidence of pediatric inflammatory bowel disease, coupled with the efficiency of whole-exome sequencing, has led to the identification of tetratricopeptide repeat domain 7A (TTC7A) as a steward of intestinal health. TTC7A deficiency is an autosomal-recessively inherited disease. In the 5 years since the original description, more than 50 patients with more than 20 distinct disease-causing TTC7A...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30553809
DOI: 10.1016/j.jcmgh.2018.12.001

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