Article

A new structural paradigm for outer membrane protein biogenesis in the Bacteroidota

2025-02-17

Abstract excerpt

In Gram-negative bacteria the outer membrane (OM) is the first line of defence against antimicrobial agents and immunological attacks. A key part of OM biogenesis is insertion of OM proteins (OMPs) by the β-barrel–assembly machinery (BAM). Here we report the cryo-electron microscopy (cryoEM) structure of a BAM complex isolated from Flavobacterium johnsoniae , a member of the phylum Bacteroidota that includes key...

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Literature Corpus work: 26391b74-246b-532a-9575-8603236c90dd
DOI: 10.1101/2025.02.17.638638

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