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Article

Outer membrane protein assembly mediated by BAM-SurA complexes.

Nature communications - 1 Sept 2024

Fenn Katherine L, Horne Jim E, Crossley Joel A, Böhringer Nils, Horne Romany J, Schäberle Till F, Calabrese Antonio N, Radford Sheena E, Ranson Neil A

Abstract excerpt

The outer membrane is a formidable barrier that protects Gram-negative bacteria against environmental threats. Its integrity requires the correct folding and insertion of outer membrane proteins (OMPs) by the membrane-embedded β-barrel assembly machinery (BAM). Unfolded OMPs are delivered to BAM by the periplasmic chaperone SurA, but how SurA and BAM work together to ensure successful OMP delivery and folding...

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Identifiers

PMID: 39218969
DOI: 10.1038/s41467-024-51358-x
PMCID: PMC11366764

Genes

OMP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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