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Article

The Structure of a BamA-BamD Fusion Illuminates the Architecture of the β-Barrel Assembly Machine Core.

Structure (London, England : 1993) - 2 Feb 2016

Bergal Hans Thor, Hopkins Alex Hunt, Metzner Sandra Ines, Sousa Marcelo Carlos

Abstract excerpt

The β-barrel assembly machine (BAM) mediates folding and insertion of integral β-barrel outer membrane proteins (OMPs) in Gram-negative bacteria. Of the five BAM subunits, only BamA and BamD are essential for cell viability. Here we present the crystal structure of a fusion between BamA POTRA4-5 and BamD from Rhodothermus marinus. The POTRA5 domain binds BamD between its tetratricopeptide repeats 3 and 4. The...

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Identifiers

PMID: 26749448
DOI: 10.1016/j.str.2015.10.030
PMCID: PMC4740259

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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