Article
Functions of the BamBCDE Lipoproteins Revealed by Bypass Mutations in BamA.
Journal of bacteriology - 8 Oct 2020
Hart Elizabeth M, Silhavy Thomas J
Abstract excerpt
The heteropentomeric β-barrel assembly machine (BAM complex) is responsible for folding and inserting a diverse array of β-barrel outer membrane proteins (OMPs) into the outer membrane (OM) of Gram-negative bacteria. The BAM complex contains two essential proteins, the β-barrel OMP BamA and a lipoprotein BamD, whereas the auxiliary lipoproteins BamBCE are individually nonessential. Here, we identify and...
Topics
- Bacterial Outer Membrane Proteins
- Escherichia coli
- Escherichia coli Proteins
- Lipoproteins
- Mutation
- Protein Folding
- Protein Multimerization
