Article

The Large Extracellular Loop of CD63 Interacts with gp41 of HIV-1 and is Essential for Establishing the Virological Synapse

2020-12-28

Abstract excerpt

Human immunodeficiency virus type 1 (HIV-1) persists lifelong in infected individuals and has evolved unique strategies in order to evade the immune system. One of these strategies is the direct cell-to-cell spread of HIV-1. The formation of a virological synapse (VS) between donor and target cell is important for this process. Tetraspanins are cellular proteins that are actively involved in the formation of a VS....

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Literature Corpus work: 26368517-523d-5c27-b07f-89646a130a00
DOI: 10.21203/rs.3.rs-124338/v1

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