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Single-cell and spatial architecture of primary liver cancer

20 Nov 2023

Abstract excerpt

Abstract Primary liver cancer (PLC) poses a leading threat to human health, and its treatment options are limited. Meanwhile, the investigation of homogeneity and heterogeneity among PLCs remains challenging. Here, using single-cell RNA sequencing, spatial transcriptomic and bulk multi-omics, we elaborated a molecular architecture of 3 PLC types, namely hepatocellular carcinoma (HCC), intrahepatic...

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PMID: 37985711
DOI: 10.1038/s42003-023-05455-0

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