Article

Deciphering Tumour Microenvironment of Liver Cancer through Deconvolution of Bulk RNA-seq Data with Single-cell Atlas

2022-11-18

Abstract excerpt

Liver cancers give rise to a heavy burden of health care worldwide. Understanding the tumour microenvironment (TME) underpins the development of precision therapy. Single-cell RNA sequencing (scRNA-seq) technology has generated high-quality cell atlases of the TME, but its wider application faces enormous costs for various clinical circumstances. Fortunately, a variety of deconvolution algorithms can instead repur...

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Literature Corpus work: 1c9e8dfd-6f5b-51e7-999a-ca2e08b20899
DOI: 10.20944/preprints202211.0344.v1

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