Article

Translatome analysis reveals cellular network in DLK-dependent hippocampal glutamatergic neuron degeneration

2024-07-12

Abstract excerpt

The conserved MAP3K12/Dual Leucine Zipper Kinase (DLK) plays versatile roles in neuronal development, axon injury and stress responses, and neurodegeneration, depending on cell-type and cellular contexts. Emerging evidence implicates abnormal DLK signaling in several neurodegenerative diseases. However, our understanding of the DLK-dependent gene network in the central nervous system remains limited. Here, we inve...

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Literature Corpus work: 260e918f-3f57-5bac-ad79-09342d100158
DOI: 10.1101/2024.07.10.602846

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