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HIPK2 in the physiology of nervous system and its implications in neurological disorders

20 Mar 2023

Abstract excerpt

HIPK2 is an evolutionary conserved serine/threonine kinase with multifunctional roles in stress response, embryonic development and pathological conditions, such as cancer and fibrosis. The heterogeneity of its interactors and targets makes HIPK2 activity strongly dependent on the cellular context, and allows it to modulate multiple signaling pathways, ultimately regulating cell fate and proliferation. HIPK2 is...

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PMID: 36935052
DOI: 10.1016/j.bbamcr.2023.119465

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