Article

SpaRx: Elucidate single-cell spatial heterogeneity of drug responses for personalized treatment

2023-08-06

Abstract excerpt

<h4>ABSTRACT</h4> Spatial cellular heterogeneity contributes to differential drug responses in a tumor lesion and potential therapeutic resistance. Recent emerging spatial technologies such as CosMx SMI, MERSCOPE, and Xenium delineate the spatial gene expression patterns at the single cell resolution. This provides unprecedented opportunities to identify spatially localized cellular resistance and to optimize the...

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Literature Corpus work: 25fd6413-1d56-5156-bc5d-ab2cd717eb53
DOI: 10.1101/2023.08.03.551911

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