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Article

Studies of the Wnt/Beta-catenin signalling pathway in chronic myeloid leukaemia

2014-01-01

Abstract excerpt

The Wnt/β-catenin signalling pathway is involved in regulating cellular transcription of numerous target genes in chronic myeloid leukaemia (CML). A previous report using granulocyte-macrophage progenitors (GMPs) showed that elevated levels of unphosphorylated (active) β-catenin, alongside mis-splicing of glycogen synthase kinase 3β (GSK3β), correlated with disease progression. It was of interest to determine if u...

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Identifiers and source

Literature Corpus work
25ed7831-3aa9-5284-8849-bb346fa87b57
DOI
10.17638/02007740
Open publication

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Studies of the Wnt/Beta-catenin signalling pathway in chronic myeloid leukaemiaDOI 10.17638/02007740
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