Article

Tumor‐infiltrating lymphocytes are a marker for microsatellite instability in colorectal carcinoma

2001-06-15

Abstract excerpt

BACKGROUND Cells with deficient DNA mismatch repair develop microsatellite instability. Extensive microsatellite instability (MSI-high) is characteristic of colorectal carcinomas in hereditary nonpolyposis colorectal carcinoma (HNPCC) and in 10–% 15% of sporadic colorectal carcinomas. Microsatellite instability-high colorectal carcinomas differ from others in important clinical and pathologic features. However, MS...

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Literature Corpus work: 25dc215c-a7ef-5462-b944-c919e5b072b3
DOI: 10.1002/1097-0142(20010615)91:12<2417::aid-cncr1276>3.3.co;2-l

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