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Current Insights into Liver Fibrosis: Epidemiological Patterns, Etiopathogenesis, Clinical Correlates, and Research Agenda

2026-06-26

Abstract excerpt

Liver fibrosis develops from chronic stress and death of hepatocytes, sustained by persistent injury, immune responses, metabolic stress, and vascular changes. Multiple cells and signaling pathways are involved, with inflammation amplifying fibrogenesis and hepatic stellate cell activation driving the process. Progressive fibrotic changes, potentially culminating in cirrhosis, contribute substantially to global mo...

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Literature Corpus work
ebb2ade6-4237-5347-ae8f-d7750e2f7da8
DOI
10.20944/preprints202606.1981.v1
Open publication

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Current Insights into Liver Fibrosis: Epidemiological Patterns, Etiopathogenesis, Clinical Correlates, and Research AgendaDOI 10.20944/preprints202606.1981.v1
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