Article

PET imaging of fibroblast activation protein alpha (FAP) detects incipient cardiotoxicity due to anthracycline chemotherapy

2023-09-05

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Anthracycline chemotherapy is associated with a risk of cardiotoxicity leading to heart disease, particularly in pediatric cancer patients. Gold standard methods of detecting cardiotoxicity are insufficiently sensitive to early damage and specific pathophysiologies driving disease. Positron emission tomography (PET) couples anatomical resolution with biochemical mechanistic...

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Literature Corpus work: 256dfdd1-4b0b-5bef-9359-61dcd407be3d
DOI: 10.1101/2023.09.03.556130

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