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Anthracycline-mediated cardiomyopathy: Basic molecular knowledge for the cardiologist

1 Jul 2014

Abstract excerpt

Anthracyclines are cytostatic antibiotics discovered almost half a century ago exerting their action through inhibition of topoisomerase II. The two most representative drugs are doxorubicin and daunorubicin and they have been proven as useful antineoplastics and are widely prescribed in daily oncology practice; unfortunately, cardiotoxicity has been a limiting factor when it comes to their use. Diverse...

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Cardiovascular Function and Risk Factors
Chemotherapy-induced cardiotoxicity and mitigation
Takotsubo Cardiomyopathy and Associated Phenomena

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 25001055
DOI: 10.1016/j.acmx.2013.08.006

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