Article

Doxorubicin induces cardiotoxicity in a pluripotent stem cell model of aggressive B cell lymphoma cancer patients

2020-04-17

Abstract excerpt

Cancer therapies have been shown to induce cardiovascular complications. The aims of this study were to establish an in vitro induced pluripotent stem cell model (iPSC) of anthracycline-induced cardiotoxicity (ACT) from patients with an aggressive form of cancer. ACT-iPSC-CM generated from individuals with CD20 + B-cell lymphoma cancer who had received high doses of DOX and suffered cardiac dysfunction were obs...

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Literature Corpus work: c86bb639-8882-51d0-8557-3661676a6889
DOI: 10.1101/2020.04.15.042424

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