Article

Multimodal memory T cell profiling identifies a reduction in a polyfunctional Th17 state associated with tuberculosis progression

2020-04-25

Abstract excerpt

Mycobacterium tuberculosis ( M . tb ) results in 10 million active tuberculosis (TB) cases and 1.5 million deaths each year 1 , making it the world’s leading infectious cause of death 2 . Infection leads to either an asymptomatic latent state or TB disease. Memory T cells have been implicated in TB disease progression, but the specific cell states involved have not yet been delineated because of the limited sc...

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Literature Corpus work: 2552faeb-de71-5f3b-8cbb-c0691557b4fe
DOI: 10.1101/2020.04.23.057828

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