Article

Esophageal epithelial cell-state transitions underlie the severity of pediatric eosinophilic esophagitis

2026-03-10

Abstract excerpt

Eosinophilic esophagitis (EoE) is a leading cause of chronic esophageal dysfunction driven by immune-mediated inflammation. Peak eosinophil count (PEC) in esophageal biopsies is routinely used to assess disease activity, and its associated molecular mechanisms have been well studied. However, PEC only partially captures overall disease severity, which is comprehensively captured by the Index of Severity for Eosino...

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Literature Corpus work: 253108e5-a11a-5132-b235-0384d77992b9
DOI: 10.64898/2026.03.07.710295

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