Article
Eosinophilic oesophagitis endotype classification by molecular, clinical, and histopathological analyses: a cross-sectional study.
The lancet. Gastroenterology & hepatology - 1 Jul 2018
Shoda Tetsuo, Wen Ting, Aceves Seema S, Abonia J Pablo, Atkins Dan, Bonis Peter A, Caldwell Julie M, Capocelli Kelley E, Carpenter Christina L, Collins Margaret H, Dellon Evan S, Eby Michael D, Gonsalves Nirmala, Gupta Sandeep K, Falk Gary W, Hirano Ikuo, Menard-Katcher Paul, Kuhl Jonathan T, Krischer Jeffrey P, Leung John, Mukkada Vincent A, Spergel Jonathan M, Trimarchi Michael P, Yang Guang-Yu, Zimmermann Nives, Furuta Glenn T, Rothenberg Marc E
Abstract excerpt
BACKGROUND: Eosinophilic oesophagitis is understood in terms of quantifiable histological, endoscopic, and molecular features. Data are scant for inter-relations of these features and their potential to identify distinct disease endotypes. We aimed to identify clinical-pathological correlations between endoscopic and histological disease variables by transcription profiling of the oesophagus of patients with...
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